Check out RLFTF it a cure for covid. Only cause I love you guys

[SmokingMonkey]

there’s ALOT of drugs and companies with “fast track “ status during corona....

very true, I've read about 3-4 other drugs that are trying to do similar things to recover and prevent, but the FDA didn't allow hospitals and doctors that AREN'T part of the trials to have access to test those other drugs. They did for RLF-100.

that says something, imo

 

[ChiSoxFan]

We are not buying this shit right?

You’re balls deep in RPRX after their killer earnings report today.

 

[PEOPLESCHICKEN]

You’re balls deep in RPRX after their killer earnings report today.

Whew! Great!

Wait what???

 

[Shanemansj13]

We are not buying this shit right?

You guys are a couple now? Strange, going to have to do half him and hers...white sox and indians. More risky than penny stocks

 

[SmokingMonkey]

in case I haven't been clear - this is a speculative gamble, no one is touting it as a sure thing around here (at least I don't think they are, lol!!!)

 

[SmokingMonkey]

looks like Phase II /III trial results should come out in the next week or so, we may find out if this is legit or not earlier than I thought

 

[The Foot]

Oh I know it’s penny... there’s always potential but there’s ALOT of drugs and companies with “fast track “ status during corona....

This is the only company working on a cure that is on a fast track. As far as I know. Have not heard of any others.

 

[The Foot]

in case I haven't been clear - this is a speculative gamble, no one is touting it as a sure thing around here (at least I don't think they are, lol!!!)

Agreed. No gaurentees.

 

[SteelersPride]

this is correct ^^^



not really, the big time investors rarely dabble in OTC unless they have inside knowledge. they aren't in the game and didn't become big timers by 'speculating'. Penny stocks are highly volatile - no big time investment group would gamble that much with people's money, or they wouldn't be around very long. The price will be a roller coaster until it either gets approved or gets denied. Any Swiss traders who had shares under .10 from months ago have been taking profits. Day traders in US are constantly buying/selling, which also causes constant ups/downs.

if you truly are interested in how the drug works and how the trials are going, watch that 40min interview I posted earlier today in this thread. More hospitals want to get the chance to trial this to keep pushing it forward, or maybe they find out it doesn't work.

if it gets approval, shots come out in Sept and inhalers come out in Oct - its the 2nd week of Aug, we have a bit to go before we find out if this is the real deal or not.

from what i've researched, if things go live with RLF-100, the stock price will land somewhere in the $5 - $20 range.

Just a sales analyst for a major global corporation over here, not a doctor/scientist/lab tech or anything like that, but from what I understand, the active agent in the drug is a synthetic version of vasoactive intestinal polypeptide, which naturally occurs in the human body already. It protects the air sacs in the cells that line all animal's lungs. So you're taking the synthetic version of what your body already produces to protect its lungs to fight off covid.

I can't tell you why some people's bodies don't produce enough of the VIPs to fight off this virus and why some do, but regardless, this drug is trying to replicate and boost what your body already does to protect your lungs.

enjoy the long read!!

Thanks for the info. I read the studies.....totally understand the drug...makes a bit more sense now , honestly.

 

[SteelersPride]

And fwiw @SmokingMonkey my earlier comments were loosely prodding at what some thought of the actual study and and it’s data from phase 1. I think...or maybe I Thought I posted it lol

 

[The Foot]

RLFTF:
MEDICAL DEVICE NEWS MAGAZINE A DIGITAL PUBLICATION FOR THE PRACTICING MEDICAL SPECIALIST, INDUSTRY EXECUTIVE & INVESTOR

RELIEF THERAPEUTICS HOLDING SA Announces Plans to Test Aviptadil for Treatment of COVID-induced Acute Respiratory Distress Syndrome
Compassionate Care Protocol to be Conducted at Rambam Healthcare Campus in Coordination with the Government of Israel COVID-19 Death is Primarily Caused by Acute Respiratory Distress Syndrome (ARDS), in Which Severe Inflammation Causes the Lungs to Fill with Fluid and is Associated with 50% Mortality Company Reports RLF-100 (Aviptadil) Has Shown Clinical Benefit in Phase 1/2 Trials of Pulmonary Arterial Hypertension, Sarcoidosis, and ARDS Relief is Initiating Proof-of-Concept Trials Khase 2 Studies to Rreat ARDS in COVID-19 Patients Who Oherwise Have Less Than a 50% Chance of Survival More information on www.clinicaltrials.gov
Wednesday, August 12, 2020

RELIEF THERAPEUTICS Holding SA reports RLF-100, acquired by Relief from Mondo Biotech, AG, has Investigational New Drug clearance from the US FDA and the European Medicines Agency for phase 2 trials in ARDS and has been awarded orphan drug designation by both agencies for the treatment of ARDS, Acute Lung Injury, and Sarcoidosis. Aviptadil is Vasoactive Intestinal Polypeptide (VIP), a naturally-occurring peptide hormone that is known to be concentrated in the lungs. VIP has been shown in five species of animal models to have a potent effect in models of ARDS and Acute Lung Injury. In these models, Aviptadil has shown potent anti-inflammatory and specifically anti-cytokine activity in the lungs.

The first clinical protocol will compare intravenous administration of Aviptadil to its administration via an endotracheal tube in patients who are already on mechanical ventilation because of ARDS. Assuming no new safety signals are detected, a second protocol will quickly be initiated to treat patients with early signs of respiratory distress in the hopes of preventing progression to ARDS and the need for mechanical ventilation.

“After carefully reviewing the preclinical and clinical data, we believe that RLF-100 has a chance to be a safe and effective treatment for Acute Respiratory Distress Syndrome in patients infected by COVID-19, who otherwise have less than 50% chance of survival, despite intensive care. The State of Israel is eager to test this potentially lifesaving treatment in patients who today have no other therapeutic option, said Dr. Halberthal. We will try every possible mechanism to help safeguard our patients in this global crisis.

“As a third-generation physician and the father of newly-trained physician, I am deeply honored to be working with longtime colleagues in Israel’s Ministry of Health on critical initiative. Owing to the rapidly expanding size of the epidemic and the extraordinary unmet medical need, we intend to initiate phase 2 clinical trials on an urgent schedule in order to bring a potentially life-saving drug to patients.”

RLF-100 (Aviptadil) is a patented formulation of Vasoactive Intestinal Polypeptide (VIP) that was originally developed and is currently marketed in Europe for the treatment of erectile dysfunction. VIP is known to be highly concentrated in the lung and to inhibit a variety of inflammatory cytokines. Aviptadil was awarded Orphan Drug Designation in 2001 by the US FDA for treatment of Acute Respiratory Distress Syndrome and in 2005 for treatment of Pulmonary Arterial Hypertension. Aviptadil was awarded Orphan Drug Designation by the European Medicines Agency in 2006 for the treatment of Acute Lung Injury and in 2007 for the treatment of Sarcoidosis. Both the US FDA and the EMEA have granted Investigational New Drug licenses for human phase 2 trials of Aviptadil.

Acute respiratory distress syndrome (ARDS) is a type of respiratory failure characterized by rapid onset of widespread inflammation in the lungs. Symptoms include shortness of breath, rapid breathing, and bluish skin coloration. Among those who survive, a decreased quality of life is relatively common.

Causes may include viral infection, sepsis, pancreatitis, trauma, pneumonia, and aspiration. The underlying mechanism involves diffuse injury to cells which form the barrier of the microscopic air sacs of the lungs, surfactant dysfunction, activation of the immune system, and dysfunction of the body’s regulation of blood clotting. In effect, ARDS impairs the lungs’ ability to exchange oxygen and carbon dioxide.

The primary treatment involves mechanical ventilation together with treatments directed at the underlying cause. The syndrome is associated with a death rate between 35 and 50%.

 

[The Foot]

Guys please understand that this is a penny stock and anything can happen. I dont want anyone to buy and get hurt by this stock. Sorry if O came off otherwise. so please use your own judgement.

I just really wanted everyone to take a look and see what you thought.

 

[Stakesarehigh]

Guys please understand that this is a penny stock and anything can happen. I dont want anyone to buy and get hurt by this stock. Sorry if O came off otherwise. so please use your own judgement.

I just really wanted everyone to take a look and see what you thought.

Ultimately everything in stocks is a gamble. If someone can't afford a thousand shares and losing Every bit of 500 dollars they shouldn't be in the market

 

[ehb5]

Not saying this won’t happen but if everyone on a fantasy football forum is on it. And the public knowledge is out there. Why isn’t everyone on this?

This is exactly right. If you think you've stumbled upon some secret massively undervalued stock that the billion dollar investment managers missed well.... you're wrong.

 

[ehb5]

Well, it's increased its value 10x on speculation. IF it actually works, it'll go higher.

Yes. But then it will crash. This is just 'the greater fool' theory at work. The idea that it's ok the stock doesn't have underlying financials driving it's increase in stock price because there will always be some other sucker to buy in at the next high...

Problem is... It doesn't work like that. This story has happened millions of times in different financial markets and it usually doesn't end too well.

 

[ehb5]

I’m no expert or even well informed, but I’d guess the “big guys” don’t bother with penny stock.

There's a good reason for that

 

[Shanemansj13]

This is exactly right. If you think you've stumbled upon some secret massively undervalued stock that the billion dollar investment managers missed well.... you're wrong.

I think you are thinking way too big here. The hope is this penny stock can get to $2-$3 possibly more. I mean that isn't out of the question but it's going to be some time with them working on trial runs, for now it's just fluctuating back and forth at a steady pace. This is a stock you hold on to for months to see if you can get a decent profit...this isn't going to get you rich.

 

[Stakesarehigh]

I think you are thinking way too big here. The hope is this penny stock can get to $2-$3 possibly more. I mean that isn't out of the question but it's going to be some time with them working on trial runs, for now it's just fluctuating back and forth at a steady pace. This is a stock you hold on to for months to see if you can get a decent profit...this isn't going to get you rich.

Nope seems it is meant to make you a few grand if played correctly on the short or upwards of 5-10 if you go all in and wait it out

 

[Shanemansj13]

Nope seems it is meant to make you a few grand if played correctly on the short or upwards of 5-10 if you go all in and wait it out

Right, that's what I'm hoping for but won't get my panties in a wad for losing a couple hundred. It will be interesting in the next month or so to see what happens

 

[gob]

Yes. But then it will crash. This is just 'the greater fool' theory at work. The idea that it's ok the stock doesn't have underlying financials driving it's increase in stock price because there will always be some other sucker to buy in at the next high...

Problem is... It doesn't work like that. This story has happened millions of times in different financial markets and it usually doesn't end too well.

Ok