I think the key for Iowa to win is field position. In their losses, they got horrible field position. The offense needs to do better. They need to waste time by chipping away 4-5 yards at a time. If they don't score, pin Ohio State's offense deep on their side of the field.
The defense showed they don't tire, but they start at midfield a lot with only a 4-play rest. If Iowa wants to pull off the upset, the offense needs to do much better.
They are sweet alt uniforms, but I like traditional, Steeler-copied uniforms. If Iowa was to win or if Jewell has a crazy good game and they showed highlights, traditional uniforms are more recognizable. Save these uniforms for Purdue or something.