Josh Gordon: Facing Suspension - Failed Drug Test

[icefreeze57]

Josh Gordon of Cleveland Browns faces season-long suspension - ESPN

Failed drug test a few months ago, potential season long suspension. Wonder if they knew this before the draft or if it is new

 

[Red_Chaos]

Josh Gordon of Cleveland Browns faces season-long suspension - ESPN

Failed drug test a few months ago, potential season long suspension. Wonder if they knew this before the draft or if it is new

Neh they knew it

 

[bluepigpen]

My Browns fans are is shock

 

[icefreeze57]

crazy, A year long suspension is BS btw

 

[Retroram52]

Dumbass kids don't know what they have been given in life and they start effin around with drugs. Can you say Darryl Henley??

 

[icefreeze57]

Dumbass kids don't know what they have been given in life and they start effin around with drugs. Can you say Darryl Henley??

Dude, it was a little pot. A little different from dealing coke and trying to kill a judge??? (Darryl Henley - Wikipedia, the free encyclopedia - quick google search for us young bucks haha)

 

[Retroram52]

Oh O.K. Ice. I suppose you are going to tell me that cannabis is good for ya. Just to let you know, I have Master's degree in Biochemistry and Molecular Biology and now the data is slowly coming out that indeed cannabis destroys long-term memory by disrupting protein folding in the brain. Sure. Cannabis is great stuff. So don't dude me with an "its only weed" line. Capeeche?

 

[icefreeze57]

No, but failing a drug test is a little different than selling coke and trying to kill someone. He isn't a bad person or going to be a failure because one failed test.

I'd like to see that study though btw

 

[Retroram52]

Why don't you go do your own research. It's on the web for all to see.

 

[shopson67]

Oh O.K. Ice. I suppose you are going to tell me that cannabis is good for ya. Just to let you know, I have Master's degree in Biochemistry and Molecular Biology and now the data is slowly coming out that indeed cannabis destroys long-term memory by disrupting protein folding in the brain. Sure. Cannabis is great stuff. So don't dude me with an "its only weed" line. Capeeche?

Alcohol kills brain cells too. Are you a teetotaler?

Cannabis also has medical uses, such as controlling seizures. Alcohol is good for cleaning, I guess.

 

[Retroram52]

I never stated Shopson that alcohol in large amounts was good for your brain. It can kill as well. And no I don't drink much at all. Are you slushhead? Perhaps so.

Yada, yada, yada about the medicinal purposes of cannabis. That's like saying I am going to sacrifice my long-term memory so I can control my seizures when there are plenty of legitimate seizure medications that do the same thing and a person's long-term memory is not destroyed.

That medicinal argument has the same validity as stating making abortion illegal will return women to back alley coat hanger abortions when there are no recorded incidents of that kind in nearly 40 years of abortion. It amazes me what people will believe to push their agenda.

 

[icefreeze57]

Why don't you go do your own research. It's on the web for all to see.

oh sorry thought you had credible research, yeah dude, I can google and find anything I want on the internet...

 

[Retroram52]

O.K. ICE. Try Marla Paul's latest research from NW University where she found abnormal brains in stoners or if you like here is a list you can read from.

1. Curran, H. W., Brignell, C., Fletcher, S., Middleton, P., Henry, J. (2002). “Cognitive and subjective dose-response effects of acute oral delta9-tetrahydrocannabinol (THC) in infrequent cannabis users.” Psychopharmacology 164(9). 61–70.
2. Riedel, G., & Davies, S. N. (2005). Cannabinoid function in learning, memory and plasticity. Handbook of Experimental Pharmacology 168, 445–477.
3. Ranganathan, M., & D’Souza, D. C. (2006). The acute effects of cannabinoids on memory in humans: A Review. Pharmacology 188, 425–444.
4. Iversen, L. (2003). Cannabis and the brain. Brain 126, 1252–1270.
5. Solowij, N., & Battisti, R. (2008). The chronic effects of cannabis on memory in humans: a review. Current Drug Abuse Reviews 1, 81–98.
6. Lambert, D. M., & Fowler, C. J. (2005). The endocannabinoid system: drug targets, lead compounds, and potential therapeutic applications. Journal of Medicinal Chemistry 48(16), 5059–5087.
7. Matsuda, L. A., Lolait, S. J., Brownstein, M. J., et al. (1990). Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 346, 561–564.
8. Munro, S., Thomas, K. L., & Abu-Shaar, M. (1993). Molecular characterization of a peripheral receptor for cannabinoids. Nature 365, 61–65.
9. Mailleux, P., Parmentier, M., & Vanderhaeghen, J. J. (1992). Distribution of cannabinoid receptor messenger RNA in the human brain: an in situ hybridization histochemistry with oligonucleotides. Neuroscience Letters 143, 200–204.
10. Piomelli, D. (2003). The molecular logic of endocannabinoid signalling. Nature Reviews Neuroscience 4, 873–884.
11. Smith, C. M. (2000). Technical knockout. The Scientist 14(15), 32
12. Varvel, S. A., & Lichtman, A. H. (2002). Evaluation of CB1 receptor knockout mice in the Morris water maze. Journal of Pharmacology and Experimental Therapeutics 301, 915–924.
13. Ledent, C., Valverde, O., Cossu, G., et al. (1999). Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. Science 283, 401–404.
14. Martin, P. D., & Shapiro, M. K. (2000). Disparate effects of long-term potentiation on evoked potentials and single CA1 neurons in the hippocampus of anesthetized rats. Hippocampus 10, 207–212.
15. Wilson, R. I., & Nicoll, R. A. (2002). Endocannabinoid signaling in the brain. Science 296, 678–682.
16. Sullivan, M. (2000). Cellular and molecular mechanisms underlying learning and memory impairments produced by cannabinoids. Learning Memory 7, 132–139.
17. Pistis, M., Porcu, G., Melis, M., et al. (2001). Effects of cannabinoids on prefrontal neuronal responses to ventral tegmental area stimulation. Neuroscience 14(1), 96–102.
18. Hajos, N., Ledent, C., & Freund, T. F. (2001). Novel cannabinoid-sensitive receptor mediates inhibition of glutamatergic synaptic transmission in the hippocampus. Neuroscience 106(1), 1–4.
19. Nicoll, R. A., & Malenka, R. C. (1995). Contrasting properties of two forms of long-term potentiation in the hippocampus. Nature 377, 115–118.
20. Bear, M. F., & Abraham, W. C. (1996). Long-term depression in hippocampus. Annual Review Neuroscience 19, 437–462.
21. Shen, M., Piser, T. M., Seybold, V. S., et al. (1996). Cannabinoid receptor agonists inhibit glutamatergic synaptic transmission in rat hippocampal cultures. Journal Neuroscience 16, 4322–4334.
22. Misner, D. L., & Sullivan, J. M. (1999). Mechanism of cannabinoid effects on long-term potentiation and depression in hippocampal CA1 neurons. Journal of Neuroscience 19(16), 6795–6805.
23. Pistis, M., Ferraro, L., Pira, L., et al. (2002). Δ9-Tetrahydrocannabinol decreases extracellular GABA and increases extracellular glutamate and dopaminelevels in the rat prefrontal cortex: an in vivo microdialysis study. Brain Research 948, 155–158.
24. Miller, L. L., & Branconnier, R. J. (1983). Cannabis: effects on memory and the cholinergic limbic system. Psychological Bulletin 93(3), 441–456.
25. Lichtman, A. H., & Martin, B. R. (1996). Delta 9-tetrahydrocannabinol impairs spatial memory through a cannabinoid receptor mechanism. Psychopharmacology Series (Berl) 119, 282–290
26. Wise, L. E., Thorpe, A. J., & Lichtman, A. H. (2009). Hippocampal CB1 receptors mediate the memory impairing effects of Δ9-tetrahydrocannabinol. Neuropsychopharmacology 34, 2072–2080.
27. Sweatt, J. D. (2004). Hippocampal function in cognition. Psychopharmacology 174, 99–110.
28. Misner, D. L., & Sullivan, J. M. (1999). Mechanism of cannabinoid effects on long-term potential and depression in hippocampal CA1 neurons. Journal Neuroscience 19, 6795–6805.
29. Shen, M., Piser, T. M., Seybold, V. S., & Thayer, S. A. (1996). Cannabinoid receptor agonists inhibit glutamatergic synaptic transmission in rat hippocampal cultures. Journal of Neuroscience 16, 4322–4334.
30. Hajos, N., Katona, I., Naiem, S. S., et al. (2000). Cannabinoids inhibit hippocampal GABAergic transmission and network oscillations. European Journal of Neuroscience 12, 3239–3249.
31. Glickfeld, L. L., & Scanziani, M. (2006). Distinct timing in the activity of cannabinoid-sensitive and cannabinoid-insensitive basket cells. Nature Neuroscience 9, 807–815.
32. Mackie, K., & Katona, I. (2009). Get stoned in GABAergic synapses. Nature Neuroscience 12(9), 1081–1083.
33. Amunts, K., Kedo, O., Kindler, M., et al. (2005). Cytoarchitectonic mapping of the human amygdala hippocampal region and entorhinal cortex: intersubject variability and probability maps. Anatomy and Embryology (Berl) 210(5–6), 343–352.
34. S. R., & Grace, A. A. (2006). Cannabinoids potentiate emotional learning plasticity in neurons of the medial prefrontal cortex through basolateral amygdala inputs. The Journal of Neuroscience 26(24), 6458–6468.
35. Laviolette, S. R., Lipski, W. J., & Grace, A. A. (2005). A subpopulation of neurons in the medail prefrontal cortex encodes emotional learning through burst and frequency codes through a dopamine D4 receptor-dependent basolateral amygdala input. Journal Neruoscience 25, 6066–6075
36. Silva de Melo, L. C., Cruz, A. P., Rios Valentim Jr, S. J., et al. (2005). Delta(9)-THC administered into the medial prefrontal cortex disrupts the spatial working memory. Psychopharmacology (Berl) 183, 54–65.
37. Egashira, N., Mishima, K., & Iwasaki, K., et al. (2002). Intracerebral microinjections of delta 9-tetrahydrocannabinol: search for the impairment of spatial memory in the eight-arm radial maze in rats. Brain Research 952, 239–245.
38. Baddeley, A. D. (1972). Retrieval rules and semantic coding in short-term memory. Psychological Bulletin, 78(5), 379–385
39. Pastötter, B., Schicker, S., Niedernhuber, J., & Bäuml, K. T. (2011). Retrieval during learning facilitates subsequent memory encoding. Journal of Experimental Psychology: Learning, Memory, and Cognition, 37(2), 287–297.
40. Ranganathan, M., & D’Souza, D. C. (2006). The acute effects of cannabinoids on memory in humans: a review. Pharmacology 188, 425–444.

There, is that credible enough for ya? Now why don't you tell me what these data say about acute and chronic cannabis use and long-term memory concerned with long-term potentiation and Excitatory Postsynaptic Potentiations, there smart guy? And don't ever question my advanced degrees and what I know about this krap again. Ya got that Ice??

 

[mutigers1fan]

Are all those names draft picks, Retro?

 

[Retroram52]

No Mutigers. They are authors of peer-reviewed science journals research that has been submitted. There are also a few books smittered in as well. Apparently IceFreeze wanted some reading material in between the next several draft rounds before tomorrow.

 

[mutigers1fan]

Yeah I knew what they were, I've had to do research on a lot of psych studies over the last few years so as far as that you were listing I knew what I was looking at, just figured I'd lighten the mood. Always way too uptight on this board.

 

[Retroram52]

What are you studying in Psych? I am an internship and a dissertation away from completing a Ph.D in Clinical Psych. I am a big Neuropsych guy and am interested in a number of areas such as the father's effect on brain development and neurotransmitter imbalances that are evident in children with an absentee father.

 

[mutigers1fan]

Just a psych minor at Mizzou, nothing too special.

 

[icefreeze57]

Retro, sorry I wasn't trying to be a dick, I know I came off that way.
I was actually asking for real research. The Marla Paul stuff I found wasn't on the topic of our discussion, but I'm reading that Wise/Thrope/Litchman study on memory affects. The reason I ask for newer studies is because of stigma and the fact that I don't think it is fairly researched in an un-biased manner.

If Gordon gets a year suspension I think that is very unfair, but the information I was missing is that I think this is not his first offense as "ESPN reported Gordon was facing a season-long suspension. But according to the league's drug policy, a player in the third stage of the league's drug program would receive an indefinite suspension, lasting at least a calendar year, for a subsequent violation. Banned players must apply for reinstatement" (USA Today). If the suspension is required, then that is the rules, and it sucks but I guess it is what it is.

But back to the "weed" conversation. I'm a decriminalization fan, not a legalization fan, I just hate wasting our resources on "cracking down" on weed when there are much worse things going on in the world and much bigger issues. I don't think it is "evil" or "deadly" but there are many cons that most people don't consider. It's a major gateway drug and is addicting, and does affect memory and all these other things (but like someone else said... so is alcohol).

I really didn't love the comparison of a drugged fail test for weed and selling/distributing coke and killing judges/witnesses whatever it is. I don't think that is a fair comparison. But again, sorry I was actaully looking for good new scholarly information suggestions and when you said I should go google it on my own time (summarizing) that normally happens because the poster is talking out their ass. Common internet forum mishap.

Go Rams!
(PS sorry for long wait - I was in NYC volunteering and celebrating and haven't checked this thread since my last comments)

 

[jacobarch]

Guys instead of arguing about whether or not marijuana is socially accepted and if the NFL is being too stringent on their players, facts are facts and rules are rules. I run my own company. I don't let people smoke on the job. While I don't drug screen because my company is too small. However, if I got wind of an employee that was doing drugs ILLEGALLY outside or inside of the workplace they would be reprimanded and eventually fired. Point is the NFL is a business and the rules are the rules and if you can't follow them you will eventually be fired.