I hate to hear that. Trent is the guy I take for granted. I hate Nsekhe at RT, I hate him at G, but he's actually not bad at LT. This is a major blow though. Trent is solid in the run game too.
I would think they will have to put a cast on his thumb. Ligaments, dislocation, possible fracture …. they take time to heal. He can play with a cast but will have to grip with his fingers.