The top-ranked Nadal, who is seeded No. 2, will start against No. 57 Martin Klizan of Slovakia. The Spaniard, who won his ninth French Open title earlier this month, could then face Lukas Rosol, who beat him here two years ago.
Nadal, the only man with at least one Grand Slam title in 10 consecutive years, could then be pitted against big-serving Ivo Karlovic in the third round. Looming in the quarterfinals could be another big hitter -- eighth-seeded Milos Raonic of Canada.