Eastbound and Down is very funny but ER was still a really good show well into its long run. I didn't even start watching it until its 6th or 7th season.
I have to really be interested in the subject matter to be able to stand dramas. Most of them come off as unintentionally funny to me at some point or another.
There have been so many fucking hospital dramas over the years, that to be honest, I have never watched a single episode of ER, and I never will either.